Look for
Close this search box.

Factors associated with therapeutic response in asthmatic children in the context of SARS-CoV-2

General Objective: To analyze the factors associated with the therapeutic response in asthmatic children from 5 to 17 years of age in the context of SARS-CoV-2.

Specific objectives

  • To describe the quality of life, economic costs and knowledge about asthma in patients from 5 to 17 years of age.
  • Identify the presence of IgG and IgM anti-SARS-Cov-2 antibodies in asthmatic patients from 5 to 17 years of age
  • Identify polymorphisms (SNPs) associated with the lack of therapeutic response to glucocorticoids and beta agonists
  • Analyze the relationship between the expression of the NR3C1, ADRB2, ADCY9 genes and the presence of IgG and IgM anti-SARS-Cov-2 antibodies.
  • Identify polymorphisms (SNPs) in the ACE2 gene associated with the progression of the disease caused by SARS-CoV-2
  • To identify barriers and facilitators in asthma self-care practices according to the perception of asthmatic patients, their caregivers and medical personnel from a qualitative phenomenological approach.
  • Design an educational piece to promote proper asthma treatment.

Participating Institutions:

UC, UDA, UIDE, UCE.

Participants:

Project Director Silvana Patricia Donoso Moscoso.

  • Silvana Patricia Donoso Moscoso
  • Dolores Susana Andrade Tenesaca
  • Vivian Alejandra Neira Molina
  • Maritza Raphaela Ochoa Castro
  • Fabiola Maytee Zavala Sanchez
  • Claudia Rosana Rodas Espinoza
  • Phillip John Cooper
  • Lucy Yadira Baldeon Rojas
  • Jorge Manuel Perez Galarza

Awarded budget: $45000

Project status: Signing of agreements.