General Objective: Develop a toxicological testing platform in zebrafish (Danio rerio) for the discovery of new environmental contaminants, the evaluation of water quality and the measurement of the effectiveness of decontamination treatments.
Specific objectives:
- Standardize toxicology and teratogenicity assays in zebrafish embryos and larvae using contaminants such as xanthates, cytostatic drugs (azathioprine) and synthetic leachates.
- Analytically evaluate the degradation and mineralization of the cytostatic drug azathioprine dissolved in water by application of the heterogeneous Fenton and H2O2/UVC advanced oxidation processes, separately and in combination.
- To evaluate the toxicity and teratogenicity of the residuals of azathioprine degradation after advanced oxidation heterogeneous Fenton and H2O2/UVC, separately and combined, using zebrafish embryos and larvae as a model.
- Analytically evaluate the removal of the contaminant load from a synthetic leachate by applying a photocatalytic process with TiO2 (anatase) deposited on sand and UVC radiation.
- To evaluate the toxicity and teratogenicity of the results after the removal of the contaminating load of leachate by application of a photocatalytic process with TiO2 deposited on sand and UVC radiation, using zebrafish embryos and larvae as a model.
Participating Institutions:
PUCE, EPN, UTA, UTM.
Participants:
Project Director MARCO ANDRÉS ROMERO CARVAJAL
- JOSÉ LUIS RIVERA PARRA
- FLORINELLA MUÑOZ BISESTI
- RODNY DAVID PEÑAFIEL AYALA
- CELIA MARGARITA MAYACELA ROJAS
- NELLY ESTHER FLORES TAPIA
- GUSTAVO ALEJANDRO ALTAMIRANO BRIONES
Awarded budget: $50000,00
Project status: In process
